02/23/2019 / By Ellaine Castillo
People often underestimate the effects that their diet has on the brain. However, there is a growing body of evidence that highlights the clear connection between the gut and the brain. This is often dubbed as the gut-brain axis.
Recent studies on this matter focused on the effects of a high-salt diet on brain health. For a long time, people have associated excessive amounts of salt with high blood pressure. This consequently increases the risk of various health problems, including heart disease and stroke. However, some data have shown that high salt intake can be linked to stroke, regardless of whether the person has high blood pressure or a high risk of heart disease. This observation suggests that there is a missing link between salt intake and brain health.
The gut-brain axis has become the center of many studies over the years. Researchers have found that the disruption of the gut-brain axis increases the risk of diseases like Parkinson’s and irritable bowel syndrome. There are also studies highlighting the effects of high salt intake on the gut and consequently, the brain. These showed that too much salt results in immune changes in the gut that make the brain more vulnerable to attacks by the body’s own immune system. Based on this, it is possible to say that the gut communicates with the brain through immune signaling.
A study published in Nature showed another connection between the gut and brain that’s mediated by the immune system. According to their findings, immune signals sent by the gut can damage blood vessels in the brain. This leads to deteriorated brain health and cognitive impairment.
The researchers arrived at these findings through in vivo studies in mice. After following a high-salt diet, the mice experienced immune responses in their gut, which triggered a cascade of chemical responses that reached the blood vessels in their brain. These effects interfered with blood flow to the parts of the brain involved with learning and memory, namely the cortex and hippocampus. As a result, the mice performed poorly in tests of cognitive performance. Fortunately, the study also shows that lowering salt intake can improve the detrimental effects of a high salt diet.
Overall, the results of these studies show that although the gut appears to be isolated from the brain, it can have significant effects on the latter. Furthermore, these findings support the idea that what you eat affects how you think.
Eating the wrong foods can cause significant damage to the brain. However, the right ones can keep the gut-brain axis healthy. Some examples of foods and nutrients that are beneficial for the gut-brain axis include the following:
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brain function, brain health, cognitive impairment, food science, gut health, gut-brain axis, immune response, mind-body medicine, research, salt, stroke
This article may contain statements that reflect the opinion of the author