Green chiretta found to relieve symptoms of the common cold

A study published in the journal Planta Medica has found that multiple oral dosing of green chiretta (Andrographis paniculata) at the normal therapeutic dose for the common cold and uncomplicated upper respiratory tract infections regulates various clinical parameters within normal ranges. In Scandinavian and Asian countries, green chiretta is widely used as a remedy for common cold, fever, and noninfectious diarrhea.

  • A team of researchers from Thailand assessed the physiological effects of short-term multiple dose consumption of a standardized green chiretta capsule used for the treatment of the common cold and uncomplicated upper respiratory tract infections.
  • For the study, the Thai research team recruited 20 healthy participants.
  • The participants orally received 12 capsules of 4.2 g of a standardized green chiretta crude powder for a period of three days.
  • They took four green chiretta capsules thrice a day with eight-hour intervals. Four capsules of green chiretta amounted to 1.4 g.
  • The results revealed that all of the measured clinical parameters, such as blood pressure, electrocardiogram, blood chemistry, hematological profiles, urinalysis, and blood coagulation, were found to be within normal ranges for a healthy person.
  • After the third day of treatment, researchers observed some changes in some parameters.
  • These included inductions of white blood cells and absolute neutrophil count in the blood, a decrease in plasma alkaline phosphatase, and an induction of urine pH.
  • The research team observed a rapid and transient decrease in blood pressure 30 minutes after the intake of green chiretta capsule. This led to a substantial decrease in mean systolic blood pressure.
  • In addition, no serious adverse events occurred during the intervention period.

Overall, the findings of the study suggest that multiple intakes of green chiretta capsule at a normal dose modulate clinical parameters within normal ranges.

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Journal Reference:

Suriyo T, Pholphana N, Ungtrakul T, Rangkadilok N, Panomvana D, Thiantanawat A, Pongpun W, Satayavivad J. CLINICAL PARAMETERS FOLLOWING MULTIPLE ORAL DOSE ADMINISTRATION OF A STANDARDIZED ANDROGRAPHIS PANICULATA CAPSULE IN HEALTHY THAI SUBJECTS. Planta Medica. 1 March 2017;83(09): 778-789. DOI: 10.1055/s-0043-104382

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